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		<title>THE HARDEST DAY</title>
		<link>http://lutfiaulia.wordpress.com/2010/11/25/25112010/</link>
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		<pubDate>Thu, 25 Nov 2010 05:14:12 +0000</pubDate>
		<dc:creator>lutfiaulia</dc:creator>
				<category><![CDATA[Uncategorized]]></category>

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		<description><![CDATA[One more day, one last look Before I leave it all behind And play the role that&#8217;s meant for us That said we&#8217;d say goodbye One more night by your side Where our dreams collide And all we have is everything And there&#8217;s no pain there&#8217;s no hurt There&#8217;s no wrong it&#8217;s all right If [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=lutfiaulia.wordpress.com&amp;blog=3310393&amp;post=14&amp;subd=lutfiaulia&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p>One more day, one last look</p>
<p>Before I leave it all behind</p>
<p>And play the role that&#8217;s meant for us<br />
That said we&#8217;d say goodbye<br />
One more night by your side<br />
Where our dreams collide<br />
And all we have is everything<br />
And there&#8217;s no pain there&#8217;s no hurt<br />
There&#8217;s no wrong it&#8217;s all right<br />
If I promise to believe will you believe<br />
That there&#8217;s nowhere that we&#8217;d rather be<br />
Nowhere describes where we are Nowhere<br />
Ive no choice, I love you Ive<br />
Leave, love you wave goodbye<br />
And all I ever wanted was to stay<br />
And nothing in this worlds gonna change, change<br />
Never wanna wake up from this night<br />
Never wanna leave this moment<br />
Waiting for you only, only you<br />
Never gonna forget every single thing you do<br />
When loving you is my finest hour<br />
Leaving you, the hardest day of my life<br />
The hardest day of my life<br />
I still breathe, I still eat<br />
And the sun it shines the same as it did yesterday<br />
But there&#8217;s no warmth, no light<br />
I feel empty inside<br />
But I never will regret a single day<br />
I know it isn&#8217;t going to go away<br />
What I&#8217;m feeling for you<br />
I will always love you<br />
Leave, love you wave goodbye<br />
And all, and all I ever wanted was to stay<br />
Nothing in this world&#8217;s gonna change&#8230;<br />
Never wanna wake up from this night<br />
Never wanna leave this moment<br />
Waiting for you only, only you<br />
Never gonna forget every single thing you do<br />
When loving you is my finest hour<br />
I never knew I&#8217;d ever feel this way<br />
I feel for you&#8230;<br />
Never wanna wake up, I feel for you, from this night<br />
Never wanna leave this moment<br />
Waiting for you only, only you Waiting<br />
Never gonna forget every single thing you do<br />
When loving you is my finest hour<br />
Leaving you, the hardest day of my life&#8230;<br />
Never wanna wake up from this night</p>
<p>﻿</p>
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		<title>TERAPY GEN DAN RNAi</title>
		<link>http://lutfiaulia.wordpress.com/2008/04/24/terapy-gen-dan-rnai/</link>
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		<pubDate>Thu, 24 Apr 2008 04:44:47 +0000</pubDate>
		<dc:creator>lutfiaulia</dc:creator>
				<category><![CDATA[Tugas Terstruktur]]></category>

		<guid isPermaLink="false">http://lutfiaulia.wordpress.com/?p=12</guid>
		<description><![CDATA[Pada 5 tahun yang lalu, sudah banyak kelompok peneliti yang memulai suatu penelitian tentang usaha teknologi di bidang biomedicine, terapi gen dan RNA interference(RNAi). Therapi gen, pada satu pihak berniat untuk menyediakan jasa untuk mengobati dengan memperkenalkan material (DNA atau RNA) menyandi suatu protein yang hilang atau cacat kedalam suatu jaringan sel pasien. Suatu tanda [...]<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=lutfiaulia.wordpress.com&amp;blog=3310393&amp;post=12&amp;subd=lutfiaulia&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
			<content:encoded><![CDATA[<p class="MsoNormal" style="text-align:justify;text-indent:42.55pt;line-height:150%;"><span style="font-size:10pt;font-family:&quot;color:black;">Pada 5 tahun yang lalu, sudah banyak kelompok</span><span style="font-size:10pt;font-family:&quot;color:black;"> peneliti</span><span style="font-size:10pt;font-family:&quot;color:black;"> yang memulai suatu penelitian tentang usaha<span> </span>teknologi di </span><span style="font-size:10pt;font-family:&quot;color:black;">bidang</span><span style="font-size:10pt;font-family:&quot;color:black;"> biomedicine, </span><span style="font-size:10pt;font-family:&quot;color:black;">terapi gen</span><span style="font-size:10pt;font-family:&quot;color:black;"> dan </span><span style="font-size:10pt;font-family:&quot;color:black;">RNA </span><span style="font-size:10pt;font-family:&quot;">interference(RNAi).</span><span style="font-size:10pt;font-family:&quot;color:black;"> Therapi gen, pada satu pihak berniat untuk menyediakan jasa untuk mengobati dengan memperkenalkan material (DNA atau<span> </span>RNA) menyandi suatu protein yang hilang atau cacat kedalam suatu jaringan sel pasien. Suatu tanda dari ilmu terapi gen adalah penyerahan yang efisien dari asam nukleat melalui suatu vektor, dapat juga nonviral, seperti liposome, atau nanopartikel, atau dari genetically virus yang dimodifikasi. Akhir-akhir ini</span><span style="font-size:10pt;font-family:&quot;color:black;">, adeno-associated</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">virus ( AAV), adenovirus (</span><span style="font-size:10pt;font-family:&quot;color:black;">Ad</span><span style="font-size:10pt;font-family:&quot;color:black;">) dan lentivirus sudah </span><span style="font-size:10pt;font-family:&quot;color:black;">banyak </span><span style="font-size:10pt;font-family:&quot;color:black;">muncul</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">pre-clinical atau studi klinis</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">pilihan serbaguna dan sempurna</span><span style="font-size:10pt;font-family:&quot;color:black;">. </span><span style="font-size:10pt;font-family:&quot;color:black;">Sebagai contoh, vector</span><span style="font-size:10pt;font-family:&quot;color:black;"> AAV</span><span style="font-size:10pt;font-family:&quot;color:black;"> adalah yang digunakan untuk membawa</span><span style="font-size:10pt;font-family:&quot;color:black;"> atau mengirim gen </span><span style="font-size:10pt;font-family:&quot;color:black;">faktor IX </span><span style="font-size:10pt;font-family:&quot;color:black;">pada manusia</span><span style="font-size:10pt;font-family:&quot;color:black;"> ke pasien dengan</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">Hemophilia B</span><span style="font-size:10pt;font-family:&quot;color:black;">,</span><span style="font-size:10pt;font-family:&quot;color:black;"> dan banyak anak-anak dengan </span><span style="font-size:10pt;font-family:&quot;color:black;">gen</span><span style="font-size:10pt;font-family:&quot;color:black;"> immunodeficiencies telah sukses</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">dengan retroviral therapy.</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">Sekalipun begitu,</span><span style="font-size:10pt;font-family:&quot;color:black;"> masih</span><span style="font-size:10pt;font-family:&quot;color:black;"> kurang baik terkait dengan vektor terbaru</span><span style="font-size:10pt;font-family:&quot;color:black;"> yang </span><span style="font-size:10pt;font-family:&quot;color:black;">menunjukkan bahwa gen therapy masih menghadapi rintangan dan</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">be</span><span style="font-size:10pt;font-family:&quot;color:black;">l</span><span style="font-size:10pt;font-family:&quot;color:black;">um berbuat sesuai dengan </span><span style="font-size:10pt;font-family:&quot;color:black;">ketentuan/perjanjian.</span></p>
<p class="MsoNormal" style="text-align:justify;text-indent:42.55pt;line-height:150%;"><span style="font-size:10pt;font-family:&quot;color:black;">P</span><span style="font-size:10pt;font-family:&quot;color:black;">ada sisi lain,</span><span style="font-size:10pt;font-family:&quot;color:black;"> RNAi</span><span style="font-size:10pt;font-family:&quot;color:black;"> menguraikan </span><span style="font-size:10pt;font-family:&quot;color:black;">tentang</span><span style="font-size:10pt;font-family:&quot;color:black;"> sequence-specific</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">silencing</span><span style="font-size:10pt;font-family:&quot;color:black;"> dari</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">ekspresi</span><span style="font-size:10pt;font-family:&quot;color:black;"> gen yang di</span><span style="font-size:10pt;font-family:&quot;color:black;">timbulkan</span><span style="font-size:10pt;font-family:&quot;color:black;"> oleh </span><span style="font-size:10pt;font-family:&quot;color:black;">RNAs </span><span style="font-size:10pt;font-family:&quot;color:black;">doublestranded pendek.</span><span style="font-size:10pt;font-family:&quot;color:black;"> P</span><span style="font-size:10pt;font-family:&quot;color:black;">ertama </span><span style="font-size:10pt;font-family:&quot;color:black;">dijelaskan pada </span><span style="font-size:10pt;font-family:&quot;color:black;">cacing, serangga dan </span><span style="font-size:10pt;font-family:&quot;color:black;">pada </span><span style="font-size:10pt;font-family:&quot;color:black;">tumbuhan</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">sebagai suatu antiviral</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">pertahanan rencana bawaan, RNA</span><span style="font-size:10pt;font-family:&quot;color:black;">i</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">yang</span><span style="font-size:10pt;font-family:&quot;color:black;"> kemudian juga</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">ditemukan akti</span><span style="font-size:10pt;font-family:&quot;color:black;">f</span><span style="font-size:10pt;font-family:&quot;color:black;"> di </span><span style="font-size:10pt;font-family:&quot;color:black;">(</span><span style="font-size:10pt;font-family:&quot;color:black;">dalam)</span><span style="font-size:10pt;font-family:&quot;color:black;"> organisme </span><span style="font-size:10pt;font-family:&quot;color:black;">yang lebih tinggi</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">(sekalipun hanya mungkin bukan bagian dari system</span><span style="font-size:10pt;font-family:&quot;color:black;"> kekebalan</span><span style="font-size:10pt;font-family:&quot;color:black;">)</span><span style="font-size:10pt;font-family:&quot;color:black;">. RNAi m</span><span style="font-size:10pt;font-family:&quot;color:black;">amali</span><span style="font-size:10pt;font-family:&quot;color:black;">a</span><span style="font-size:10pt;font-family:&quot;color:black;"> dan manusia mulai </span><span style="font-size:10pt;font-family:&quot;color:black;">jalan </span><span style="font-size:10pt;font-family:&quot;color:black;">di dalam</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">inti</span><span style="font-size:10pt;font-family:&quot;color:black;"> (nukleus)</span><span style="font-size:10pt;font-family:&quot;color:black;">, </span><span style="font-size:10pt;font-family:&quot;color:black;">ekspresi dari </span><span style="font-size:10pt;font-family:&quot;color:black;">microRNAs (miRNAs).</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">Di dalam</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">suatu</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">enzymatic kompleks,</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">mereka di</span><span style="font-size:10pt;font-family:&quot;color:black;">bagi di dalam precusor</span><span style="font-size:10pt;font-family:&quot;color:black;"> miRNAs, mengekspor </span><span style="font-size:10pt;font-family:&quot;color:black;">ke </span><span style="font-size:10pt;font-family:&quot;color:black;">cytoplasm</span><span style="font-size:10pt;font-family:&quot;color:black;">a</span><span style="font-size:10pt;font-family:&quot;color:black;">, diproses lebih lanjut<span> </span>oleh Dicer nuclease, dan</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">kemudian</span><span style="font-size:10pt;font-family:&quot;color:black;"> disatukan</span><span style="font-size:10pt;font-family:&quot;color:black;"> dengan suatu multiprotein kompleks (RNA</span><span style="font-size:10pt;font-family:&quot;color:black;"> induced </span><span style="font-size:10pt;font-family:&quot;color:black;">silencing</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">kompleks [ RISC]) bersama-sama dengan suatu target mRNA.</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">Micr</span><span style="font-size:10pt;font-family:&quot;color:black;">oRNA</span><span style="font-size:10pt;font-family:&quot;color:black;">s sering mempunyai berbagai urutan</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">tidak se</span><span style="font-size:10pt;font-family:&quot;color:black;">suai</span><span style="font-size:10pt;font-family:&quot;color:black;"> dengan target mereka dan mempengaruhi silencing</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">s</span><span style="font-size:10pt;font-family:&quot;color:black;">ebagai</span><span style="font-size:10pt;font-family:&quot;color:black;"> suatu </span><span style="font-size:10pt;font-family:&quot;color:black;">mekanisme </span><span style="font-size:10pt;font-family:&quot;color:black;">translational yang tak</span><span style="font-size:10pt;font-family:&quot;color:black;"> di</span><span style="font-size:10pt;font-family:&quot;color:black;">kenal.</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">Bagaimanapun,</span><span style="font-size:10pt;font-family:&quot;color:black;"> mereka </span><span style="font-size:10pt;font-family:&quot;color:black;">meningkatkan laporan miRNAs dengan sempurna</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">mRNA target</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">complementaras dan kemampuan untuk m</span><span style="font-size:10pt;font-family:&quot;color:black;">emicu degradasi.semua ini</span><span style="font-size:10pt;font-family:&quot;color:black;"> dipercaya</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">bahwa beratus-ratus miRNAs boleh</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">disandikan di </span><span style="font-size:10pt;font-family:&quot;color:black;">(</span><span style="font-size:10pt;font-family:&quot;color:black;">dalam) </span><span style="font-size:10pt;font-family:&quot;color:black;">genom </span><span style="font-size:10pt;font-family:&quot;color:black;">manusia dan bahwa</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">beribu-ribu gen mungkin diatur </span><span style="font-size:10pt;font-family:&quot;color:black;">sampai dua mekanisme </span><span style="font-size:10pt;font-family:&quot;color:black;">pada level tertent</span><span style="font-size:10pt;font-family:&quot;color:black;">u.</span><span style="font-size:10pt;font-family:&quot;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">Sesungguhnya, dengan cepat sejumlah<span> </span>laporan yang terus meningkat sedang</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">membuktikan </span><span style="font-size:10pt;font-family:&quot;color:black;">potensi </span><span style="font-size:10pt;font-family:&quot;color:black;">RNA</span><span style="font-size:10pt;font-family:&quot;color:black;">i</span><span style="font-size:10pt;font-family:&quot;color:black;"> untuk menindas </span><span style="font-size:10pt;font-family:&quot;color:black;">gen</span><span style="font-size:10pt;font-family:&quot;color:black;"> manapun,</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">dari selular oncogenes</span><span style="font-size:10pt;font-family:&quot;color:black;"> </span><span style="font-size:10pt;font-family:&quot;color:black;">atau gen</span><span style="font-size:10pt;font-family:&quot;color:black;"> yang</span><span style="font-size:10pt;font-family:&quot;color:black;"> disebabkan kuman virus</span><span style="font-size:10pt;font-family:&quot;color:black;">.</span></p>
<p class="MsoNormal" style="text-align:justify;line-height:150%;"><span style="font-size:10pt;font-family:&quot;color:black;"><!--[if !supportEmptyParas]--> <!--[endif]--></span></p>
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<p class="MsoNormal" style="line-height:150%;"><span style="font-size:10pt;font-family:&quot;color:black;">Nama<span> </span>: Lutfi Aulia</span></p>
<p class="MsoNormal" style="line-height:150%;"><span style="font-size:10pt;font-family:&quot;color:black;">NIM <span> </span>: O1A005087</span></p>
<p class="MsoBodyTextIndent" style="margin-left:0;text-align:left;text-indent:0;" align="left"><span>Email<span> </span>: <a href="mailto:http//hose_geka@yahoo.com">http//hose_geka@yahoo.com</a></span></p>
<p class="MsoBodyTextIndent" style="margin-left:0;text-align:left;text-indent:0;" align="left"><span>Blog<span> </span>: http/lutfiaulia.wordpress.com</span></p>
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		<title>Hello world!</title>
		<link>http://lutfiaulia.wordpress.com/2008/03/29/hello-world/</link>
		<comments>http://lutfiaulia.wordpress.com/2008/03/29/hello-world/#comments</comments>
		<pubDate>Sat, 29 Mar 2008 04:36:11 +0000</pubDate>
		<dc:creator>lutfiaulia</dc:creator>
				<category><![CDATA[Uncategorized]]></category>

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		<description><![CDATA[ pren.. gw lutfi aulia..farmasi 2005 &#8230;niey blog ptama gw..lam kenal kubuat blog ini demi bioteknologi farmasi&#8230;sekian..wassalam<img alt="" border="0" src="http://stats.wordpress.com/b.gif?host=lutfiaulia.wordpress.com&amp;blog=3310393&amp;post=1&amp;subd=lutfiaulia&amp;ref=&amp;feed=1" width="1" height="1" />]]></description>
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<p> pren.. gw lutfi aulia..farmasi 2005 &#8230;niey blog ptama gw..lam kenal</p>
<p>kubuat blog ini demi bioteknologi farmasi&#8230;sekian..wassalam</p>
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